Talk:Protein biosynthesis

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Article editing for Coursework - Update[edit]

Hi all, now that I've finished with my edits to the page I'd like to thank anyone who assisted in editing the article and the addition of the GIF. The now aim/structure of the article is that the lead section provides sufficient detail and is accessible to a GCSE student. The rest of the details in the article are to the level of A-level with various extensions to include some degree level content e.g the section on types of glycosylation or sickle cell anaemia and figures to support visual learners throughout. Kep17 (talk) 11:08, 17 April 2020 (UTC)

Article editing for Coursework[edit]

Hi all, I'm a final year life sciences student at Imperial College London. For part of my Science Communication coursework, we have been tasked with improving a Wikipedia article. Based on your comments and the analysis by Wikipedia, I have chosen this article to improve. My goals are to edit/re-write this article to make it coherent, logical and streamlined, I'm specifically aiming to make this article accessible to GCSE and A-level students as Protein Biosynthesis is a core part of many curricula - for context, the textbooks referenced in this article are undergraduate level despite protein biosynthesis being a core concept in Biology. In addition, I will be adding my own illustrations to try and make it easier to understand. Any comments or suggestions would be appreciated Kep17 (talk) 15:51, 3 March 2020 (UTC)


following translation you are bound to run in circles. translation (genetic) really deserves a page of it's own. Kku 11:43 Jan 10, 2003 (UTC)

language is very disorganized[edit]

I agree with many users that this article is impossible to read. While I make no particular claim to expertise in the subject matter, anyone with a middle schooler's grasp of English can plainly see that the writing style is utterly contrary to scholarly writing. The introduction is a rambling presentation of numerous facts and arguments which are unrelated to each other and which do not introduce the topic. While the introduction could potentially be rewritten to be grammatically and structurally sound, I suspect that the facts themselves have merely been picked from the body for arbitrary reasons. I recommend the article be tagged as in need of editing or numerous issues. (talk) 18:18, 20 April 2015 (UTC)

Post-translational modification[edit]

I can see how you'd be confused, Dominus, but I can also understand why the article would be worded that way, as there are different post-translational modification processes involving different chemical/structural changes, and if a protein is not chemically modified, then PTMs are irrelevant. Perhaps it would clarify things to word the statement as follows: "Proteins may undergo post-translational modification, including the formation of disulfide bridges or attachment of any of a number of biochemical functional groups." Just in case you were wondering the post translational modification of proteins occurs in the Golgi Apparatus... Rena Silverman 16:04, 17 September 2007 (UTC)

Post-translational modification[edit]

The article says:

Many proteins undergo post-translational modification.

Don't all proteins undergo post-translational modification to remove the methionine unit that is always present at the initial end of the strand after it is manufactured by the ribosome? -- Dominus 16:07, 9 May 2004 (UTC)

needs pictures[edit]

Some pictures would really help this article. -- 20:21, 5 June 2006 (UTC)

I have to agree that some pictures or even animated diagrams would help--ManInStone 10:07, 6 July 2007 (UTC)

By now, ANYTHING WOULD HELP!!!!!!!! --Heero Kirashami (talk) 06:29, 29 November 2007 (UTC)


diagram incorrect[edit]

not being a clever biologist myself at my GCSEs, i couldn't help but notice that the diagram "The chemical process of connecting two amino acids resulting in a dipeptide and a water molecule" was incorrect.

Water, being H²O, is connected up as H-O-H, but is connected as a right angle, so more like

O -- H


Stwalkerster 19:14, 20 September 2006 (UTC)

Water is a lot more than the diagram above as well. For the purpose of this article, a representation of HOH is adequate, as we are more interested in the nature of the dipeptide. Water as a matter of fact is joined at and angle of 105 degrees... just correcting the previous error...

not understandable[edit]

this article and the ones under it like transcription are not understandable to me, a scientist not trained in biology. they assume more knowledge than many interested readers will have. they jump right into arcane technical details without giving upfront motivation. --Rmalloy 04:46, 8 October 2006 (UTC)

hey, you're a scientist not trained in biology. me, I'm just a smart minor who is trying to understand this stuff.--Heero Kirashami (talk) 06:31, 29 November 2007 (UTC)

i have been trying to figure outt how long this process is. its an important part to this article. if any1 knows plz let me no. my email is thx<3 —Preceding unsigned comment added by (talk) 21:53, 6 March 2008 (UTC)


Why doesn't this article contain information about Translation? It seems to be that this is the most important step of protein biosynthesis (that is to say, it is the step that immediately results in a protein). Malignon 16:25, 8 March 2007 (UTC)

I just added a section on translation... but it may be a bit long and probably needs some editing... if someone could look it over please! :) -ComCC 01:38, 18 April 2007 (UTC)

Strange use of words[edit]

What is the scientific background behind the sentence; "The amino acids are then loaded onto tRNA trains for use in the process of journeying forth to the world beyond."? I think this should be removed. —Preceding unsigned comment added by Lozzaaa (talkcontribs) 13:44, 24 February 2008 (UTC)


Since the translation section was in odd language and was signed with a book and publisher, assuming copyvio - quick fix replaced with lead section from Translation (biology) Leevanjackson (talk) 01:48, 24 March 2008 (UTC)

Merge Proposal[edit]

I propose the merger of the "Protein synthesis" page into "Protein biosynthesis".

From a Wikipedia Operational perspective:

Both pages are marked "It has been suggested that this article or section be merged with ..." but I see no discussion of the merger. Nor were the merger "Discuss" link set up (I've now set them up). Am I missing something?

From a merits of merging perspective:

"Protein synthesis" makes no mention of artificial synthesis. The "Protein" page references "Protein synthesis". "Protein" has a "Chemical synthesis" section. A Google search sent me to "Protein synthesis".

Assuming that the interested parties concur; I volunteer to perform a quick, and not too clean, merge of the two articles. The article resulting from the merge will still require a good deal of work.

At 6:00pm, reading a New York Time genetics article, I looked up "Coding region (Biology)" in Wikipedia and have been Wikipedia-ing since. It is now midnight and I have a headache.

--Deicas (talk) 07:10, 6 April 2009 (UTC)


I added a redirect from the page "proteosynthesis" as this term showed up as a synonym for Protein synthesis in a couple of papers I read recently. It is not that common of a term as far as I can see. Colincbn (talk) 05:59, 3 September 2009 (UTC)

Protein synthesis inhibitors[edit]

Hello. I just wanted to note that the while Protein synthesis inhibitors redirects here (or used to redirect here), there is in fact a Protein synthesis inhibitor article out there. I've modified the redirect but perhaps some here will find it appropriate to merge back here the content of the Protein synthesis inhibitor article. Pichpich (talk) 22:23, 12 April 2010 (UTC)

Article should be merged with Central Dogma[edit]

Both articles contain almost identical information and protein synthesis is a part of the Central Dogma

--Arafitos (talk) 00:55, 18 January 2011 (UTC)


One of the references is by "Jeremy, Ron", and the "Molecular Biology of the White Girl", by Vivid, on a link on I'm guessing this is not correct...

The articles Gene expression and Protein biosynthesis are similar[edit]

Both the articles refer to the same thing. I see no dissimilarities. The ultimate goal of gene expression is protein synthesis. These two articles are like seeing a snake from its mouth and from the tail. So I propose to merge the two articles. This message will also be posted on Gene expression article. --G.Kiruthikan (talk) 13:57, 1 March 2014 (UTC)

Assessment comment[edit]

The comment(s) below were originally left at Talk:Protein biosynthesis/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

high school/SAT biology content and important MCB overview/intro to transcription, translation etc.; changed rating from high to top - tameeria 15:17, 18 February 2007 (UTC)

Last edited at 15:17, 18 February 2007 (UTC). Substituted at 03:28, 30 April 2016 (UTC)

wrong syntax[edit]

"Phenomena of RNA synthesis from DNA template In transcription an mRNA chain"

this doesn't look right